Researchers in the field of anti-aging medicine have demonstrated that caloric restriction leads to activation of the Sirtuin 1 (SIRT 1) gene, leading to improved insulin sensitivity and antithrombotic effects. Activation of sirtuins also enhance DNA repair, genome stability, induction of apoptosis, and improved longevity in eukaryotes.  The phytochemical Resveratrol activates the SIRT1 gene, leading to all the benifical metabolic effects mentioned above.

A study just published in Metabolic Syndrome and Related Disorders demonstrated that Resveratrol improved left ventricular function in patients with type 2 diabetes that had suffered from a Infarct Myocadial Acute (IMA).

Reference

Cacciapuoti, F. Opposite Effects of Metabolic Syndrome and Calorie Restriction on Thrombotic Disease: Head and Tail of Same Coin—Resveratrol’s Role. Metabolic Syndrome and Related Disorders. Ahead of print, available only online.

http://www.liebertonline.com/doi/abs/10.1089/met.2008.0057