Published by dsdinternational on 23 Oct 2008 at 07:02 am
Serum Homocysteine, Cortisol and Ascorbate
This study published by Cascalheira in Ann Nutr Metab found that elevated serum homocysteine was correlated with elevated cortisol, and decreased levels of serum ascorbate and folate.
“High serum levels of homocysteine and cortisol are independent risk factors for several pathologies and their levels can be regulated by some vitamins (folate, B12, B6, etc. ). Serum homocysteine levels correlate positively with cortisol and age, and negatively with ascorbate and folate . A negative correlation between serum levels of cortisol and ascorbate was also observed. Multiple linear regression analysis showed that the best independent predictors of serum homocysteine concentration were cortisol age and folate…. the highest tertile of homocysteine concentration has also higher cortisol (p < 0.005) and lower ascorbate (p < 0.05) concentrations compared with the lowest tertile of homocysteine concentration. Conclusion: The association between serum concentrations of homocysteine, cortisol and ascorbate suggests interaction between circulating levels of these molecules.”
Reference
http://content.karger.com/produktedb/produkte.asp?doi=158636